/reference/drugs/local-anesthetics

Local Anesthetics

Lidocaine, bupivacaine, ropivacaine, mepivacaine, chloroprocaine

Amide local anesthetic / class IB antiarrhythmic

Blocks voltage-gated Na⁺ channels in nerves (LA) and cardiac myocytes (antiarrhythmic).

Amide local anesthetic, long-acting

Voltage-gated Na⁺ channel blocker. Higher protein binding and lipid solubility than lidocaine → longer duration but greater cardiotoxicity.

Amide local anesthetic, long-acting

S-enantiomer of propivacaine. Less lipid-soluble than bupivacaine → less cardiotoxicity but slightly less potency.

Education only — not a substitute for current package inserts or clinical judgment. Always confirm doses.