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/reference/drugs/local-anesthetics
Local Anesthetics
Lidocaine, bupivacaine, ropivacaine, mepivacaine, chloroprocaine
Launch catalog target: 13 drugs. 3 with full clinical detail below.
Lidocaine
XylocaineAmide local anesthetic / class IB antiarrhythmic
Blocks voltage-gated Na⁺ channels in nerves (LA) and cardiac myocytes (antiarrhythmic).
Bupivacaine
Marcaine · SensorcaineAmide local anesthetic, long-acting
Voltage-gated Na⁺ channel blocker. Higher protein binding and lipid solubility than lidocaine → longer duration but greater cardiotoxicity.
Ropivacaine
NaropinAmide local anesthetic, long-acting
S-enantiomer of propivacaine. Less lipid-soluble than bupivacaine → less cardiotoxicity but slightly less potency.
Education only — not a substitute for current package inserts or clinical judgment. Always confirm doses.