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OR Cardiac Arrest
ACLS adapted for the operating room: anesthetic depth, surgical bleeding/positioning/embolism are reversible causes the medicine code team won't think of first.
Recognition
- •Loss of pulse on art line / pulse ox / ETCO₂ drop
- •Asystole, PEA, V-fib/V-tach on monitor
- •Sudden bradycardia → arrest in MH, LAST, sympathectomy
Steps
- 1Call code, start CPR (100–120/min, depth 5 cm), 100% O₂
- 2Reduce/stop volatile + vasodilatorsAnesthetic depth is a uniquely OR cause.
- 3Surgical pause + control hemorrhageSurgeon should pack + apply pressure; turn off insufflation.
- 4Reposition supine + LUD if pregnantProne CPR is feasible if access prevents repositioning.
- 5Standard ACLS drugs at standard doses (except LAST + bupivacaine)
- 6Reverse causes — Hs/Ts + OR-specificHypovolemia, hypoxia, H⁺ acidosis, hypo/hyperkalemia, hypothermia, tension pneumo, tamponade, toxins (anaphylaxis, MH, LAST), thrombosis (PE/MI), trauma.
- 7TEE if available for cause + monitoring response
- 8Consider ECMO if refractory + reversible cause
Drugs + doses
| Drug | Dose | Note |
|---|---|---|
| Epinephrine | 1 mg IV q3–5 min (standard; ≤100 mcg in LAST) | |
| Amiodarone | 300 mg IV bolus, then 150 mg | |
| Calcium chloride | 1 g IV (hyperkalemia, CCB toxicity) | |
| Bicarb | 1 mEq/kg (severe acidosis, hyperkalemia, TCA OD) |
Pitfalls
- !If patient was just induced — anesthetic depth is the cause until proven otherwise.
- !Code team will not know about the surgical site; you must direct.
- !EtCO₂ < 10 during CPR predicts poor outcome — push harder, give vasopressor.
Sources
- AHA ACLS 2020 Update
- Moitra Anesth Analg 2018
- Society Cardiothoracic Anesthesia Cardiac Arrest
Anatomy reference
Sourced reference images. 4 matches for "heart cardiac chambers ventricle".
Browse the full image library →Education only — not a substitute for facility protocols, MOC certification, or clinical judgment. Always follow your institutional crisis algorithm and confirm doses against current package inserts.



